Microfluidic Membrane Devices for Real Time Blood Plasma Separation

Abstract

This work investigates the design and the operation of microfluidic membrane devices aimed at
the real-time separation of blood plasma. The goal is to enhance separation accuracy and response time for
point-of-care diagnostic devices. A hybrid approach that included computational modeling and experimental
validation was used. Results indicate higher plasma purity and recovery efficiency compared to conventional
centrifugation techniques. The study demonstrates the promise of microfluidic devices in the field of medical
diagnostic devices, offering an infrastructure for real-time, automated, and low-impact plasma extraction