Process Optimization of Filtration in Crystallization-Based Product Recovery

Abstract

This work investigates the integration of filtration with crystallization processes toward
recovering products in fine chemical production. A novel dual vacuum-pressure driven hybrid filtration
system was designed and studied. Statistical modeling along with practical testing validated temperature,
filter media, particle size, and other process variables selected to be optimized. The enhanced process yield
was improved by 25% and cycle time decreased by 30% when compared to baseline methods. These findings
emphasize the importance of integrating filtration with crystallization and the need for these techniques to be
more easily adopted into the chemical manufacturing sector for enhanced energy efficiency.